Comparison of two doses of Dexmedetomidine as an adjuvant to Bupivacaine 0.5% in USG guided Supraclavicular Brachial Plexus Block: A Double Blind Randomised controlled study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 99
- 试验地点
- 1
- 主要终点
- To compare the efficacy of two doses of Dexmedetomidine as an adjuvant to Bupivacaine 0.5% in ultrasound-guided supraclavicular brachial plexus block in upper limb surgery
研究概览
简要总结
This randomised double blinded controlled study aims to compare the two doses of Dexmedetomidine as an adjuvant to Bupivacaine 0.5% in USG guided supraclavicular brachial plexus block.A total of 60 Patients will be enrolled and divided in to three groups.
The primary outcome will be assessed by hemodynamic parameters like HR,SBP,DBP,MAP,SPO2 at baseeline and at every 5mins for 1hour and 15mins till completion of surgery.The secondary outcome will be assessed using Pinprick method,modified bromage scsle,Sedation score,VAS score,complications like local anaaesthesia toxicity,phrenic nerve palsy,subcutaneous emphysema and pneumothorax.The goal is to evaluate comparison of efficacy of analgesia in two doses of Dexmedetomidine to Bupivacaine in upper limb surgeries
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing elective upper limb surgery.
- •Age between 18 to 65 years.
- •ASA physical status class 1 and 2.
排除标准
- •History of allergy or hypersensitivity to local anaesthetic Local infection at the site of injection Refusal to consent Patients with coagulation disorders Pregnancy Morbid obesity History of coronary artery disease, chronic renal and hepatic disease Seizure disorder Psychiatric disease.
结局指标
主要结局
To compare the efficacy of two doses of Dexmedetomidine as an adjuvant to Bupivacaine 0.5% in ultrasound-guided supraclavicular brachial plexus block in upper limb surgery
时间窗: To compare the duration of analgesia
次要结局
- 1. To compare the onset and duration of sensory and motor block 2. To compare the rescue analgesic requirements in 24hrs(3.To compare the intraoperative sedation score)
研究者
Adithya V
School of medical sciences and research Sharda hospital Sharda university