Airway disease in older people

Not Applicable

Completed

• Conditions: Asthma in older people; Chronic Obstructive Pulmonary Disease (COPD) in older people; Respiratory - Asthma; Respiratory - Chronic obstructive pulmonary disease

• Registration Number: ACTRN12606000414516
• Lead Sponsor: Woolcock Institute of Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-09-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

For asthmatic subjects: Inclusion criteria are doctor diagnosis of asthma, and FEV1 ³ 50% predicted.
For COPD subjects: Inclusion criteria are doctor diagnosis of COPD, 15 pack year smoking history, FEV1 ³ 50% predicted.

Exclusion Criteria

Asthmatic exclusion criteria: are current smoking, or > 10 pack year history of smoking, respiratory infection or prednisone use in the last 4 weeks.
COPD exclusion criteria are current smoking and respiratory infection in the last 4 weeks.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Conducting airway ventilation heterogeneity are assessed on each patient[Ventilation heterogeneity is measured at the start of the visit];Dose response ratio to methacholine challenge test assessed on each patient[The methacholine challenge test is conducted immediately after the ventilation heterogeneity is measured]