Goal-Directed Fluid Management Based on Non- Invasive Monitoring of Pulse Oximeter-Derived Pleth Variability Index
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Complication
- Sponsor
- University of California, Irvine
- Enrollment
- 334
- Locations
- 1
- Primary Endpoint
- Duration of hospital stay
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to evaluate whether goal directed fluid management using respiratory variations in the oxygen saturation by pulse oximetry (SpO2) waveform has potential to decrease postoperative complications and outcomes.
Detailed Description
The aim of this study is to test the hypothesis that monitoring and minimizing the respiratory variations in the pulse oximeter waveform amplitude by volume loading has potential to decrease postoperative morbidity and length of stay in the hospital in patients undergoing routine, moderate-risk elective surgery. In this study the investigators will test the impact of hemodynamic optimization based on the respiratory variations in the plethysmographic waveform amplitude to decrease postoperative morbidity and length of stay in the hospital in patients undergoing routine, moderate-risk elective surgery. The primary outcome variable is the incidence of postoperative complications. Secondary outcome variables are the duration of hospital and ICU stays, postoperative mortality, and cost of surgery.
Investigators
Maxime Cannesson
Associate Professor
University of California, Irvine
Eligibility Criteria
Inclusion Criteria
- •Patients (male or female)
- •Over 18 years old undergoing non-cardiac surgery
- •Weight \> 40 kg, Body Mass Index \< 40
Exclusion Criteria
- •Patients who do not consent
- •Body Mass Index \> 40
Outcomes
Primary Outcomes
Duration of hospital stay
Time Frame: Maximum 90 days after surgery
The length of stay in the hospital is defined as postoperative number of days in the hospital until discharge.