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Therapy for Cancer at Stomach and Esophagous junctio

Not Applicable
Conditions
Health Condition 1: null- Patients with resectable Carcinoma Gastroesophageal junction without clinical metastasis
Registration Number
CTRI/2018/05/013757
Lead Sponsor
Dr Shivendra Singh
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

All patients with resectable and hitologically proven adenocarcinoma of Gastroesophageal junction(type I,II,III) who are fit for surgery(ECOG performance status 0,1,2); No Distant metastasis on PET scan and Staging Laparoscopy

Exclusion Criteria

Distant metastasis on Staging Laparoscopy or on PET scan; refusal for informed consent for procedure; locally unresectable tumors; tumors falling in stage cT1N0 on Endoscopic ultrasound examination

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Comparison of median survival rates in patient treated with NACT followed by surgery with NACTRT followed by surgeryTimepoint: 30 days from surgery ; 3 month; 6 month; 1 year; 3 years ; 5 years
Secondary Outcome Measures
NameTimeMethod
Pathological response; Progression free survival; number of R0 resections; treatment toxicity; quality of lifeTimepoint: 30 days from surgery ; 3 month; 6 month; 1 year; 3 years ; 5 years
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