Different Doses of Intravenous Administered Dexamethasone Effecting Brachial Plexus Supraclavicular Block

Not Applicable

Not yet recruiting

• Conditions: End Stage Renal Failure
• Interventions: Drug: supraclavicular block with 20mls of Ropivacaine 0.5% and Intravenous administered dexamethasone

• Registration Number: NCT06389617
• Lead Sponsor: Hospital Universiti Sains Malaysia

Brief Summary

To compare the analgesic properties of ultrasound guided supraclavicular block using ropivacaine 0.5% in arteriovenous fistula creation when used in combination with intravenous administered dexamethasone at 4mg and 8 mg as an adjuvant

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-04
• Study First Submitted: 2024-04-24
• Study First Submitted QC: 2024-04-24
• Last Update Submitted: 2024-04-24
• Study First Posted: 2024-04-29
• Last Update Posted: 2024-04-29
• Study Start: 2024-05-01
• Primary Completion: 2024-11-30
• Study Completion: 2024-12-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Adult, age 18 to 65 years End stage renal disease patients for AV fistula creation

Exclusion Criteria

Not suitable candidate as determined by the primary team Refusal for brachial plexus block History of allergy to dexamethasone or local anesthesia Pregnancy History of previous brachial plexus injury Coagulopathy Local skin site infection Known neuropathy involving the arm undergoing surgery Patients with glucose reading more then 12mmol/

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
GROUP DF	supraclavicular block with 20mls of Ropivacaine 0.5% and Intravenous administered dexamethasone	supraclavicular block with 20mls of Ropivacaine 0.5% and Intravenous dexamethasone 4mg
GROUP DE	supraclavicular block with 20mls of Ropivacaine 0.5% and Intravenous administered dexamethasone	supraclavicular block with 20mls of Ropivacaine 0.5% and Intravenous dexamethasone 8mg

Primary Outcome Measures

Name	Time	Method
To compare the difference of onset time between sensory and motor block of supraclavicular block between ropivacaine with IV dexamethasone 4mg and ropivacaine with IV dexamethasone 8mg	2 days
To compare the difference in duration of analgesia between supraclavicular block with ropivacaine and IV dexamethasone 4mg with ropivacaine and IV dexamethasone 8mg	2 days

Secondary Outcome Measures

Name	Time	Method
To compare the duration difference of the return of motor block between supraclavicular block using ropivacaine with IV dexamethasone 4mg and ropivacaine with IV dexamethasone 8mg	2 days