ebulized naloxone in methadone poisoning

Phase 2

Recruiting

• Conditions: T40.3; Opioid, Methadone, Poisoning, naloxone infusion, Nebulized naloxone.; Poisoning by, adverse effect of and underdosing of methadone

• Registration Number: IRCT20120629010133N4
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 29 August 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Methadone Overdose
>18 and <60
Response to naloxone
Opioid dependency
Spontaneous respiration

Exclusion Criteria

No consent to participate
nasal congestion
Current catching cold
Apnea
Intubation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
O2 Saturation. Timepoint: On admission, then each hour till 6 hours, then each 3 hours. Method of measurement: Pulse oxymetery.;PCo2. Timepoint: On admission, then each hour till 6 hours, then each 3 hours. Method of measurement: Blood gasometery.;Level of consiousness using Glasgow Coma Scale. Timepoint: On admission, then each hour till 6 hours, then each 3 hours. Method of measurement: Physical Examination.

Secondary Outcome Measures

Name	Time	Method
Withdrawal Syndrome using COWS scale. Timepoint: Each 3 hours. Method of measurement: Examination.