ISRCTN39653756已完成未知
Open, multi-centre, randomised controlled trial of cardiac output-guided fluid therapy with low dose inotrope infusion compared to usual care in patients undergoing major elective gastrointestinal surgery
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 2,502
研究概览
简要总结
2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/30647034 protocol (added 12/02/2020)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Age 65 years and over
- •2. Patients undergoing major elective surgery involving the gastrointestinal tract that is expected to take longer than 90 minutes
排除标准
- •1. Inability or refusal to provide patient consent
- •2. Clinician refusal (including intention to monitor cardiac output from the start of surgery regardless of study group allocation)
- •3. American Society of Anesthesiologists (ASA) score of I
- •4. Patients expected to die within 30 days
- •5. Acute myocardial ischaemia within 30 days prior to randomisation
- •6. Acute pulmonary oedema within 30 days prior to randomisation
- •7. Contra-indication to low-dose inotropic medication
- •8. Pregnancy at time of enrolment
- •9. Previous enrolment in the OPTIMISE II trial
- •10. Current participation in another clinical trial of a treatment with a similar biological mechanism or primary outcome measure
研究者
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