Chronic Granulomatous Disease Study in China

• Conditions: Granulomatous Disease, Chronic

• Registration Number: NCT02231996
• Lead Sponsor: Shanghai Children's Medical Center

Brief Summary

CGD is a rare inherited primary immunodeficiency which is caused by the defect in one of the subunits of NADPH oxidase complex.We tend to collect and analyze Chinese CGD patients who are diagnosed in hospitals affiliated to Shanghai Jiao Tong University School of Medicine, including clinical feature, laboratory data and genetic information. we aim to find out clinical, distribution, genetic characteristic of CGD in Chinese population, etc., thus further improving the level of diagnosis and treatment for CGD.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-08-29
• Status Verified: 2014-09
• Study Start: 2014-09
• Study First Submitted QC: 2014-09-01
• Last Update Submitted: 2014-09-03
• Study First Posted: 2014-09-04
• Last Update Posted: 2014-09-05
• Primary Completion: 2016-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• x-linked and AR-linked Chronic Granulomatous Disease
• history of life-threatening severe infections
• A functional assay demonstrating abnormal NADPH oxidase function or clinical history consistent with CGD

Exclusion Criteria

• Presence of other primary immunodeficiency syndromes that do not meet the clinical and laboratory criteria for CGD.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
times of pneumonia	2 years

Trial Locations

Locations (1)

Shanghai children's medical center; 🇨🇳 Shanghai, Shanghai, China