IRCT20190806044451N2
Completed
Phase 3
Evaluation of the effects of combination therapy of pentoxifylline and losartan in comparison with losartan alone on diabetic nephropathy
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Condition 1: Type 2 Diabetes. Condition 2: Diabetic Nephropathy.
- Sponsor
- Zanjan University of Medical Sciences
- Enrollment
- 60
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Type 2 diabetic patients treated with insulin and oral agents
- •GFR above 30 cc / min / 1\.73 m2
- •albuminuria above 300 mg/g
Exclusion Criteria
- •Patient dissatisfaction
- •Type 1 diabetes
- •Pentoxifylline allergy
- •Chronic heart failure
- •Uncontrolled hypertension
- •Other medicines that affect albuminuria
- •Cerebral hemorrhage
- •Extensive retinal hemorrhage
- •ESRD, GFR \<30
- •Hyperkalemia (high potassium) 5\.5 before or during the study)
Outcomes
Primary Outcomes
Not specified
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