The effect of combination therapy of human chorionic gonadotropin ampoule (HCG) and Letrozole tablet on spermogram parameters in obese men with idiopathic infertility
- Conditions
- Male idiopathic infertility.Male infertility
- Registration Number
- IRCT20100614004181N9
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 45
Obese men with a body mass index greater than 30
Idiopathic infertility
Age 20 to 45 years
Men with informed consent
Men with a history of genital surgery
Men with a history of infectious disease in the genital system
Men with symptoms of urinary or genital infection
Men with a history of suspected contact or urethritis symptoms
Men with spermatogenesis-damaging drugs such as Sulfasalazine
Men with history of tobacco and alcohol or drugs consuming
Men with a family history of infertility in first degree relatives
Men with testicular atrophy
Men with varicocele
Men with changes in consistency and size of cord and vasodefran and epididymis
Men with abnormalities in hormone or renal and liver tests
Obese men with age less than 20-year old
Obese men with age more than 45-year old
Men without informed consent
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sperm indices including sperm volume evaluation, sperm count, motility rate and sperm morphology. Timepoint: One day before treatment and 3 months after treatment. Method of measurement: Spermogram test.
- Secondary Outcome Measures
Name Time Method Serum levels of testosterone. Timepoint: One day before treatment and 3 months after treatment. Method of measurement: Evaluation of venous blood sample based on laboratory kit.;Serum levels of estradiol. Timepoint: One day before treatment and 3 months after treatment. Method of measurement: Evaluation of venous blood sample based on laboratory kit.