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Clinical Trials/NCT07239180
NCT07239180Not yet recruitingNot Applicable

Clinical Evaluation of Tunneled Coronally Advance Flap (TCAF) Versus Modified Coronally Advanced Tunnel With Connective Tissue Graft in Management of Single Recession Defects (RT2): A Randomized Clinical Trial

Cairo University0 sites24 target enrollmentStarted: December 14, 2025Last updated:
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Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
24
Primary Endpoint
Gingival Recession Depth (GRD)
Study OverviewStudy DesignEligibility CriteriaArms & InterventionsOutcomesInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The technique under investigation aims to provide effective root coverage while offering the advantage of being less invasive.

Detailed Description

Limited RCTs have been found in the literature comparing the root coverage capacity of the tunneled coronally advanced flap versus modified coronally advanced tunnel combined with connective tissue graft in single RT2 defects. So, this trial aims to fill this gap of knowledge.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Patients with single RT2 gingival recession defect ≥ 2 mm
  • •Age >18 years old.
  • •Systemically healthy patients with no contraindications for periodontal surgeries.
  • •Gingival and plaque index less than 20%.
  • •No previous surgeries at the defect site.
  • •Accepts 6 months follow-up period (compliant patients).

Exclusion Criteria

  • •RT1 gingival recession.
  • •Smokers >10 cigarettes a day a contraindicating for any plastic periodontal surgery.
  • •Poor oral hygiene.
  • •Active periodontitis patients.
  • •Patients on medications causing gingival enlargement.
  • •Pregnancy.
  • •Teeth mobility ≥ 1 mm.
  • •Patients using fixed or removable orthodontic appliances.
  • •Restoration and/or periapical radiolucency at the defect site.

Arms & Interventions

Modified Coronally Advanced Tunnel with Connective Tissue Graft

Active Comparator

Intervention: Modified Coronally Advanced Tunnel with Connective Tissue Graft (Procedure)

Tunneled Coronally Advance Flap (TCAF) with Connective Tissue Graft

Experimental

Intervention: Tunneled Coronally Advance Flap with Connective Tissue Graft (Procedure)

Outcomes

Primary Outcomes

Gingival Recession Depth (GRD)

Time Frame: 6 months

Measuring gingival recession depth (GRD) using UNC Periodontal probe in millimeter (mm)

Secondary Outcomes

  • The Distance between the contact point and the top of the papilla (DCP)(6 months)
  • Gingival Recession Width (RW)(6 months)
  • Probing Pocket Depth (PPD)(6 months)
  • Clinical Attachment Level (CAL)(6 months)
  • Gingival Index (GI)(6 months)
  • Plaque Index (PI)(6 months)
  • Keratinized Tissue Width (KTW)(6 months)
  • Root Coverage Esthetic Score (RES)(6 months)
  • The Distance between the contact point and the top of the papilla (DCP)(6 months)
  • Probing Pocket Depth (PPD)(6 months)
  • The Percentage of Mean Root Coverage (MRC %)(6 months)
  • Complete Root Coverage (CRC)(6 months)
  • Gingival Recession Width (RW)(6 months)
  • Clinical Attachment Level (CAL)(6 months)
  • Gingival Index (GI)(6 months)
  • Keratinized Tissue Width (KTW)(6 months)
  • Plaque Index (PI)(6 months)
  • Gingival Thickness (GT)(6 months)
  • Postoperative Patient Satisfaction (Visual Analogue Scale)(6 months)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Khaled Hashem Kamal

Bachelor Degree

Cairo University

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