Coronally Advanced Flap in Combination With Acellular Dermal Matrix With or Without Enamel Matrix Derivatives for Root Coverage
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- the percentage of root coverage
研究概览
简要总结
The aim of this study is to compare the clinical outcomes of root coverage procedures, using coronally advanced flap in combination with acellular dermal matrix with or without enamel matrix derivatives .
详细描述
coverage of gingival recession defects has been considered as a matter of interest for dental practitioners.subjects with a paired gingival recession defect will be selected from the patients who sought dental treatment at our department.Random allocation of the treatment sites to test (CAF+ EMD+ADM) and control (CAF + ADM) groups will be performed by a person who is external to the study and using a computerized selection of random numbers for allocation of the study groups.The parameters of the study are as following items: probing depth( PD), clinical attachment level (CAL), width of keratinized tissue (WKT), recession depth from cemento- enamel junction (RD), recession width (RW), distance between mucogingival junction and the stent (MGJ), Plaque (PI) and gingival (GI) indices and root coverage percentage (RC) and the patients will be followed up for 6 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Having no systemic disease affecting the periodontium,
- •No contraindication for elective surgery,
- •Adequate oral hygiene ,
- •No previous surgical attempts for root coverage at the studying sites,
- •Vital teeth and signing a witness letter.
排除标准
- •Smoking, presence of a restorations on tooth surface for test and control teeth,
- •Pregnancy,
- •Being under treatment with steroids,
- •Peri-apical infection,
- •Indication for antibiotic prophylaxis prior to dental treatments
结局指标
主要结局
the percentage of root coverage
时间窗: at baseline, 2 and 6 months after treatment.
次要结局
- clinical attachment level, width of keratinized gingiva ant the position of mucco-gingival junction following root coverage procedures(6 months after treatment)