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Clinical Trials/NCT03199118
NCT03199118
Completed
Not Applicable

The Use of Coronally Advanced Flap and Subepithelial Connective Tissue Graft With or Without Platelet Rich Fibrin in the Treatment of Miller Class I or II Gingival Recession: a Randomized Clinical Trial

Cairo University1 site in 1 country28 target enrollmentJanuary 1, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Gingival Recession
Sponsor
Cairo University
Enrollment
28
Locations
1
Primary Endpoint
Recession Depth
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

This research will be conducted in an attempt to achieve complete root coverage with physiologic probing depth and a harmonious view with the adjacent tissues using Platelet rich fibrin in conjunction with Coronally advanced flap and subepithelial connective tissue graft.

Detailed Description

The study population will be divided into 2 groups: Group 1: Patients suffering from Miller class I or II gingival recession will be treated with a coronally advanced flap in conjunction with a sub-epithelial connective tissue graft. The patients should be non-smoker, medically free and above 18 years Group 2: Patients suffering from Miller class I or II gingival recession will be treated with a coronally advanced flap in conjunction with a sub-epithelial connective tissue graft and platelet rich fibrin. the patients should meet the same inclusion criteria mentionned above.

Registry
clinicaltrials.gov
Start Date
January 1, 2018
End Date
December 31, 2019
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sarah Elbanna

Assistant lecturer in the oral medicine and periodontology department

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Patients 18 years and older 2) Buccal recession defects classified as either Miller class I or II gingival recession.
  • Clinical indication and/or patient request for recession coverage 4) Good oral hygiene

Exclusion Criteria

  • Miller Class III and IV gingival recession. 2) Any systemic diseases or any medication. 3) Pregnancy. 4) Patients undergoing radiotherapy. 5) Handicapped and mentally retarded patients. 6) Current and former smokers as smoking is a contra-indication for plastic periodontal surgery .
  • Teeth with cervical restorations, abrasion

Outcomes

Primary Outcomes

Recession Depth

Time Frame: baseline-3 months-6 months

measured from the cemento-enamel junction to the margin of the gingiva at the mid-buccal point of the teeth at basline, 3 months and 6 months. It is recorded in millimeters (mm) with lower values mean better outcome.

Secondary Outcomes

  • Post Operative Pain(after 2 weeks from surgery)
  • Clinical Attachment Level(baseline-3 months-6 months)
  • Recession Width(baseline-3 months-6 months)
  • Root Coverage Gain(at 6 months)
  • Probing Depth(baseline-3 months-6 months)
  • Patient Satisfaction(questionnaire given to the patient 6 months after the surgery)
  • Root Coverage Esthetic Score (RES)(6 months)
  • Gingival Biotype(baseline-3 months-6 months)
  • Width of Keratinized Gingiva(baseline-3 months-6 months)

Study Sites (1)

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