Evaluation of Subepithelial Connective Tissue Graft Versus Acellular Dermal Matrix With Tunnel Technique in Treatment of Multiple Gingival Recessions

Not Applicable

• Conditions: Gingival Recession
• Interventions: Biological: Acellular Dermal Matrix; Procedure: Tunnel technique with the subepithelial connective tissue graft

• Registration Number: NCT02916186
• Lead Sponsor: Cairo University

Brief Summary

The goal of the present study is to compare the amount of root coverage resulting from subepithelial connective tissue graft and acellular dermal matrix associated with tunnel technique among patients suffering from multiple gingival recession.

Detailed Description

Acellular dermal matrix with Tunnel technique will offers great advantages for patients with multiple gingival recession as regards decrease surgical time, Post-Operative pain and root coverage, clinical attachment level, width of Keratinized gingiva, gingival biotype compared to subepithelial connective tissue graft with Tunnel technique.

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Status Verified: 2016-09
• Study First Submitted: 2016-09-21
• Study First Submitted QC: 2016-09-26
• Last Update Submitted: 2016-09-26
• Study First Posted: 2016-09-27
• Last Update Posted: 2016-09-27
• Study Start: 2016-10
• Primary Completion: 2017-09
• Study Completion: 2017-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

• Subjects with facial multiple gingival recession defects classified as either class I or II defects according to Miller's classification (Miller 1985).
• Subjects aged between 18 - 60 years old.
• Patients should be free from any systemic disease that may affect normal healing of tissue, and predictable outcome.
• Patients with good oral hygiene.

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Exclusion Criteria

• Current and former smokers.
• Pregnant females.
• Subjects received any periodontal therapy for minimum of 6 months prior to the study.
• Subjects taking drugs known to interfere with wound healing.
• Subjects with unacceptable oral hygiene with plaque index >2.
• Teeth with non-carious cervical lesions (NCCL), cervical caries and malalignment.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
subepithelial connective tissue graft	Acellular Dermal Matrix	Tunnel is prepared and sub-epithelial connective tissue graft is harvested from the palate and placed under the flap.
subepithelial connective tissue graft	Tunnel technique with the subepithelial connective tissue graft	Tunnel is prepared and sub-epithelial connective tissue graft is harvested from the palate and placed under the flap.
Tunnel technique with acellular dermal matrix	Acellular Dermal Matrix	the tunnel technique involves separation of the gingiva, then acellular dermal matrix interposed between the flap and the root surface.
Tunnel technique with acellular dermal matrix	Tunnel technique with the subepithelial connective tissue graft	the tunnel technique involves separation of the gingiva, then acellular dermal matrix interposed between the flap and the root surface.

Primary Outcome Measures

Name	Time	Method
patient Satisfaction .	1 year	measured by VAS scale

Secondary Outcome Measures

Name	Time	Method
root coverage	1 year	measured by periodontal probe
Gingival Bio-type	1 year	measured by endodontics file
Width of Keratinized Tissue	1 year	measured by periodontal probe
Clinical Attachment Level	1 year	measured by periodontal probe