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Clinical Trials/NCT03095378
NCT03095378
Completed
Not Applicable

Evaluation of Root Coverage by Subepithelial Connective Graft Associated to Root Conditioning by Citric Acid Plus Tetracycline and Antimicrobial Photodynamic Therapy: A Randomized Clinical Trial

University of Sao Paulo1 site in 1 country14 target enrollmentMarch 10, 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Gingival Recession
Sponsor
University of Sao Paulo
Enrollment
14
Locations
1
Primary Endpoint
Total root coverage measured with a periodontal probe in mm
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The aim of this study was to evaluate the effect of two root-conditioning agents used in conjunction with subepithelial connective graft technique on root coverage outcomes. One is citric acid plus tetracycline and the other is antimicrobial photodynamic therapy.

Detailed Description

Citric acid plus tetracycline has properties of root surface decontamination, surface demineralization and exposure of collagen fibers. Antimicrobial photodynamic therapy has been widely used in Periodontics to obtain reduction of periodontopathogenic bacteria with absence of systemic side effects and minimal bacterial resistance. Also, it has properties of root demineralization and exposure of collagen fibers. These properties may enhance root coverage in procedures of subepithelial connective graft.

Registry
clinicaltrials.gov
Start Date
March 10, 2014
End Date
March 10, 2017
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Carla Andreotti Damante

Associate professor

University of Sao Paulo

Eligibility Criteria

Inclusion Criteria

  • Gingival recession - Miller's class I or II (2 to 5 mm of height) at least in one tooth
  • Indication of root coverage by dentin hypersensitivity or esthetic

Exclusion Criteria

  • Pregnancy
  • Systemic medication use that could impair wound healing or surgery procedure
  • Systemic diseases as diabetes, uncontrolled hypertension, coagulation diseases, kidney diseases.

Outcomes

Primary Outcomes

Total root coverage measured with a periodontal probe in mm

Time Frame: one year

Distance from cemento-enamel junction to gingival margin = 0 mm

Secondary Outcomes

  • Keratinized mucosa width measured with a periodontal probe in mm(one year)
  • Dentin hypersensitivity measured by applying an air jet on teeth and patient fills up a visual analogue scale(one year)

Study Sites (1)

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