Reducing unnecessary admissions for chest pain with the Manchester Acute Coronary Syndromes (MACS) decision rule
- Conditions
- Topic: Cardiovascular, Injuries and EmergenciesSubtopic: Cardiovascular (all Subtopics), Injuries and Emergencies (all Subtopics)Disease: Injuries and Emergencies, Congenital Heart Disease and Pulmonary HypertensionCirculatory SystemAcute ischaemic heart disease, unspecified
- Registration Number
- ISRCTN86818215
- Lead Sponsor
- Central Manchester University Hospitals NHS Trust (CMFT) (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
Consenting patients, over 18 years of age, presenting to the ED with pain, discomfort or pressure in the chest, epigastrium, neck, jaw, or upper limb without an apparent non-cardiac source (compatible with the American Heart Association case definitions), which the treating physician believes warrants investigation for a possible acute coronary syndrome.
Target Gender: Male & Female; Upper Age Limit 150 years ; Lower Age Limit 18 years
1. Peak symptoms occurred more than 24 hours prior to presentation
2. Another medical condition necessitating hospital admission
3. Definite ST elevation myocardial infarction needing immediate revasularisation
4. No capacity to provide informed consent
5. Inability to communicate in English language if translation services are unavailable
6. Prisoners
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Successful early discharge, defined as a decision to discharge from the ED within 4 hours of arrival; Timepoint(s): Assessed once (can be assessed from 30 days after randomisation) (Primary clinical outcome).
- Secondary Outcome Measures
Name Time Method