Prophylactic tributyrin supplementation in acute pancreatitis

Phase 2

Recruiting

• Conditions: acute pancreatitis; acute pancreatic inflammation; 10015674; 10004018

• Registration Number: NL-OMON56163
• Lead Sponsor: Sint Antonius Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 92

Inclusion Criteria

acute pancreatitis, defined as two or more of the following criteria:
- abdominal pain
- serum amylas or lipase more than three times the upper limit
- evidence of acute pancreatitis on abdominal CT

Exclusion Criteria

-Pancreatitis due to ERCP, malignancy, trauma
-Post-operative pancreatitis
-Intra-operative diagnosis
-Immunocompromised patients (history or current immunosuppressive treatment
such as chemotherapy, radiotherapy, longer use of immunosuppressive medication
or recent high doses, immunocompromised illness* such as AIDS, leukemia,
lymphoma)
-Pregnancy and/or lactation
-Age <18 years old
-History of recurrent or chronic (MANNHEIM criteria) pancreatitis
- >72 hours since onset of symptoms

Study & Design

• Study Type: Interventional
• Study Design: Not specified