Tyrosine supplementation in preventing the cognitive effects of psychosocial stress

Phase 4

• Conditions: Stress; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12611000357954
• Lead Sponsor: Dr Lanny Bochsler

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-04-06
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Healthy adult volunteers

Exclusion Criteria

Past or present mental illness
Family history of mental illness
Any medication or illicit substance use
Pregnant

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in neurocognition as measured by neurocogntive tests battery including simple and choice reaction time, verbal episodic memory, groton maze learning task[To be measured during one day of testing - at baseline, immediately following administration of Trier Social Stress Test and again one hour later]

Secondary Outcome Measures

Name	Time	Method
Change in biochemical markers of stress (salivary cortisol and alpha-amylase) and central dopamine activity (serum prolactin)[To be measured during one day of testing - at baseline, immediately pre- and post-administration of Trier Social Stress Test and again one hour later]