Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer

Completed

• Conditions: Long-term Effects Secondary to Cancer Therapy in Adults; Colorectal Cancer; Cognitive/Functional Effects

• Registration Number: NCT00410618
• Lead Sponsor: University of Arizona

Brief Summary

RATIONALE: Learning about the long-term effects of chemotherapy and radiation therapy on brain function may help doctors plan cancer treatments.

PURPOSE: This clinical trial is looking at the neurological effects of chemotherapy and radiation therapy in patients with colon cancer.

Detailed Description

OBJECTIVES:

Primary

* Identify the nature and long-term ramifications of CNS injury as a result of cancer treatment in patients with colon cancer.

Secondary

* Analyze differences in cognitive measures and MRI data in these patients.

* Correlate MRI measures with cognitive performance in these patients.

OUTLINE: Patients undergo cognitive performance assessment and MRI.

PROJECTED ACCRUAL: A total of 42 patients will be accrued for this study.

Study Timeline

• Study Start: 2003-04
• Primary Completion: 2006-08
• Study Completion: 2006-08
• Study First Submitted: 2006-12-11
• Study First Submitted QC: 2006-12-11
• Study First Posted: 2006-12-13
• Status Verified: 2012-08
• Last Update Submitted: 2018-07-03
• Last Update Posted: 2018-07-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Nature and long-term ramifications of CNS injury as a result of cancer treatment

Secondary Outcome Measures

Name	Time	Method
Differences in cognitive measures and MRI data
Relationship between MRI measures and cognitive performance

Trial Locations

Locations (1)

Arizona Cancer Center at University of Arizona Health Sciences Center; 🇺🇸 Tucson, Arizona, United States