The Effect of ESPB on Intraoperative Hemodynamics in VATS

Not Applicable

Completed

• Conditions: Heart Rate; Erector Spinae Plane Block; Video-Assisted Thoracoscopic Surgery; Mean Arterial Pressure
• Interventions: Procedure: Postperative Erector spinae plane block; Procedure: Preoperative Erector spinae plane block

• Registration Number: NCT05334628
• Lead Sponsor: Ankara City Hospital Bilkent

Brief Summary

Video-assisted thoracic surgery (VATS) is frequently applied in thoracic surgery operations. VATS has become the standard procedure in minor and major lung surgeries. In recent years, regional anesthesia techniques have also been frequently applied to patients for pain relief. Thoracic paravertebral block (TPVB), erector spinae plane block (ESPB), and serratus anterior plane block (SAPB) are also among the regional anesthesia techniques frequently used in thoracic surgery.

General anesthesia (GA) is the main method of anesthesia for thoracic surgery. However, GA can only inhibit the projection system of the cortical limbic system or hypothalamic cortex. GA cannot completely block the transmission of peripheral noxious stimulus to the central nervous system and cannot effectively inhibit the intraoperative stress response. With the addition of peripheral blocks such as TPVB, ESPB, and SAPB, more stable hemodynamics is expected by providing preemptive analgesia in patients. As a result of all these; In this study, we aimed to compare the intraoperative hemodynamic changes of patients who underwent preoperative ESPB in patients who will undergo VATS resection under GA with those who underwent postoperative ESPB.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-11
• Study First Submitted: 2022-04-11
• Study First Submitted QC: 2022-04-12
• Study First Posted: 2022-04-19
• Primary Completion: 2022-09-12
• Status Verified: 2022-10
• Study Completion: 2022-10-12
• Last Update Submitted: 2022-10-12
• Last Update Posted: 2022-10-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Age between 18 and 80 years
• American Society of Anesthesiologists physical status I-II-III
• Body mass index between 18-40 kg/m2
• Patients undergoing elective video assisted thoracoscopic surgery

Exclusion Criteria

• Advanced cancer
• History of chronic analgesic therapy
• History of local anesthetic allergy
• Infection in the intervention area
• Patients with bleeding disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Postperative Erector Spinae Plane Block	Postperative Erector spinae plane block	In the postoperative period, under general anesthesia, after the linear ultrasound (US) probe will be placed 2-3 cm lateral to the T5 spinous process, 30 ml of 0.25% bupivacaine hydrochloride will be injected into the interfacial space below the erector spinae muscle, above the transverse process.
Preoperative Erector Spinae Plane Block	Preoperative Erector spinae plane block	In the preoperative period, under general anesthesia, after the linear ultrasound (US) probe will be placed 2-3 cm lateral to the T5 spinous process, 30 ml of 0.25% bupivacaine hydrochloride will be injected into the interfacial space below the erector spinae muscle, above the transverse process.

Primary Outcome Measures

Name	Time	Method
Mean arterial pressure	Perioperative period	Mean arterial pressure values will be recorded before anesthesia, before surgical incision, after surgical incision at 5th, 30th, 60th, 90th, 120th minutes, and after general anesthesia.
Heart rate	Perioperative period	Heart rate values will be recorded before anesthesia, before surgical incision, after surgical incision at 5th, 30th, 60th, 90th, 120th minutes, and after general anesthesia.

Secondary Outcome Measures

Name	Time	Method
Pain scores	First 24 hours after surgery	Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at the 1st, 2nd, 4th, 12th, and 24th hours after surgery.

Trial Locations

Locations (2)

Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital; 🇹🇷 Keçiören, Ankara, Turkey

Ankara City Hospital; 🇹🇷 Çankaya, Ankara, Turkey