Erector Spinae Plane, Paravertebral Versus Intercostal Nerve Block for VATS Surgery

Not Applicable

Completed

• Conditions: Thoracic
• Interventions: Other: Regional analgesia of thoracic surgical patients

• Registration Number: NCT05091398
• Lead Sponsor: Tanta University

Brief Summary

The optimal analgesia method in video-assisted thoracoscopic surgery (VATS) remains controversial. 105 patients scheduled to undergo video-assisted thoracic surgery under general anesthesia will be included. Patients will be randomly allocated to receive ultrasound-guided ESP blocks on T4 and T6 levels (Group ESPB, n = 35),PVB (Group PVB, n = 35) after the anesthesia induction and turning the patient in the lateral position or (Group ICNB, n=35) with 30 mL 0.5% bupivacaine +50 µ adrenaline will be injected by the surgeon through the thoracoscope .

Detailed Description

Standard general anesthesia was applied Patients will be randomly allocated to receive single shot of ESP blocks (Group ESPB), Paravertebral blocks (Group PVB) or (Group ICNB )at T4 and T6 levels according to a random number list that will be generated by a computer and will be stored in sealed envelopes. An independent experienced anesthesiologist will perform the first two blocks or surgeon will perform the third one through the thoracoscope according to the random number. The study coordinator, attending anesthesiologist, data collection resident and the patients will be all blinded to the treatment group assignment. All blocks will be applied on patient's back in a lateral position. Postoperative analgesia regimen consisted of a continuous infusion of iv iboprofen and morphine as a second rescue drug. Demographic data, past medical history, surgical and anesthetic data will be documented. Postoperative pain scores, consumption of analgesia and quality of recovery will be recorded to evaluate the analgesic effect.

Study Timeline

• Study First Submitted: 2021-10-01
• Study First Submitted QC: 2021-10-13
• Study First Posted: 2021-10-25
• Study Start: 2021-11-05
• Status Verified: 2022-01
• Primary Completion: 2022-01-10
• Study Completion: 2022-01-10
• Last Update Submitted: 2022-01-11
• Last Update Posted: 2022-01-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

• ASA I and II patients
• Thoracic surgery

Exclusion Criteria

• Coagulation defect

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group II	Regional analgesia of thoracic surgical patients	ultrasound-guided paravertebral block on T4 and T6 levels after the anesthesia induction and turning the patient in the lateral position
Group I	Regional analgesia of thoracic surgical patients	ultrasound-guided erector spinae block on T4 and T6 levels after the anesthesia induction and turning the patient in the lateral position
Group III	Regional analgesia of thoracic surgical patients	ultrasound-guided intercostal nerve block on T4 and T6 levels after the anesthesia induction and turning the patient in the lateral position

Primary Outcome Measures

Name	Time	Method
end tidal sevoflurane	150 minutes	intraoperative end tidal sevoflurane

Secondary Outcome Measures

Name	Time	Method
Blood pressure	150 minutes	Intraoperative blood pressure in mmHg

Trial Locations

Locations (1)

Mona Mohamed Mogahed; 🇪🇬 Tanta, Elgharbia, Egypt