Effectiveness of hyaluronic acid for the treatment of interstitial cystitis

Phase 2

• Conditions: Interstitial cystitis / bladder pain syndrome.; Interstitial cystitis (chronic)

• Registration Number: IRCT20130811014330N5
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 24

Inclusion Criteria

Older than 18 years’ old
Previously treated with a daily 25 mg of Amitriptyline for at least 1 month, and did not show any improvement in symptoms.

Exclusion Criteria

History of bacterial cystitis in the last 3 months
History of active genital herpes
History of vaginal cervical or uterine cancer
History of diverticulum
History of cyclophosphamide consumption
History of bladder tuberculosis
History of abdomen or pelvis radiotherapy
Vaginitis symptoms
History of bladder stones
History of symptom relief with antimicrobials or anticholinergics
Frequency of urination less than 8 times a day
History of benign or malignant bladder tumors

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of urination. Timepoint: Baseline, 1 week, 1 month, and 3 months after intervention. Method of measurement: the O`Leary-Sant questionnaire.;Urgency. Timepoint: Baseline, 1 week, 1 month, and 3 months after intervention. Method of measurement: the O`Leary-Sant questionnaire.;Nocturia. Timepoint: Baseline, 1 week, 1 month, and 3 months after intervention. Method of measurement: the O`Leary-Sant questionnaire.;Dysuria. Timepoint: Baseline, 1 week, 1 month, and 3 months after intervention. Method of measurement: the O`Leary-Sant questionnaire.