Assessment of Body Composition and Physical Function in Older Adults With Obesity
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Body Composition
- Sponsor
- Pennington Biomedical Research Center
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Fat Mass
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Sarcopenia, which is the loss of muscle mass and strength or physical function, naturally occurs in aging. In sarcopenic obesity, growth of muscle mass and increments in strength do not parallel weight gain, and places older adults at increased risk of falls, fractures, physical disability, frailty, and mortality from too low muscle strength relative to body size. The goal of the study is to assess body composition and physical function in older adults with obesity.
Detailed Description
This is a cross-sectional study in 40 adults aged 60 to 80 years with obesity. Body composition, physical function, and insulin resistance will be measured. Subjects who satisfy the eligibility criteria and sign the informed consent will be enrolled. Subjects will complete an assessment of body composition by bioelectrical impedance analysis and tests of physical performance. Blood will be drawn for measurement of fasting glucose and insulin.
Investigators
Candida Rebello
Assistant Professor
Pennington Biomedical Research Center
Eligibility Criteria
Inclusion Criteria
- •Body mass index \> 30kg/m2
- •Age 60 - 80 years
Exclusion Criteria
- •self-reported history of diabetes, or cancer or significant cardiovascular or hepatic or renal disease or dysfunction.
- •clinically significant gastrointestinal malabsorption syndromes such as chronic diarrhea, or celiac disease.
Outcomes
Primary Outcomes
Fat Mass
Time Frame: One day
Measurement of fat mass
Fat-free Mass
Time Frame: One day
Measurement of fat-free mass
Modified Physical Performance Test
Time Frame: One day
Test for assessing physical performance. The scale ranges from 0 to 36 and higher score indicates a better outcome
Secondary Outcomes
- Hand Grip Strength(One day)
- 6-minute Walk Test(One day)
- Homeostasis Model Assessment of Insulin Resistance (HOMA-IR)(One day)