Identification of novel periodontal disease biomarkers using miRNA expression in saliva

Asan Medical Center0 个研究点目标入组 18 人开始时间: 待定最近更新: 2019年3月11日

适应症

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•A. Advanced Periodontal Disease
•- Patients with chronic advaced periodontitis
•- Patients required primary treatment of periodontal scaling, subgingival curettage, and agreed with the basic periodontal therapy based on the standard protocol
•- subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing
•B. Mild Periodontal Disease
•- Patients with chronic initial periodontitis
•- Patients required primary treatment of periodontal scaling, subgingival curettage, and agreed with the basic periodontal therapy based on the standard protocol
•- subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing
•- Healthy periodontal patients ( more than 20 permanent teeth are present , in all parts of deep periodontal pockets measuring 4mm or less, and height is 2mm or less clinical attachment person)
•- subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing

•- Received periodontal treatment within the last six months
•- recently taken antibiotics within 3 months if you need a prescription antibiotic prophylaxis
•- taking the drug can affect periodontal status for a long period of time
•- pregnant or breastfeeding
•- In case of oral inflammatory mucosal disease (Lichen planus, etc.)
•- Patients with a history of alcoholism or drug abuse
•- other special systemic disease (high blood pressure)
•- ages under 18

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