Cognitive Training in Heart Failure Study (CogTrain-HF)
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Congestive Heart Failure
- 发起方
- Universität des Saarlandes
- 入组人数
- 107
- 试验地点
- 2
- 主要终点
- Training effects
- 状态
- 已完成
- 最后更新
- 6年前
概览
简要总结
The daily routine in clinical settings often showed cognitive impairments in patients with congestive heart failure, particularly in terms of executive functions, episodic memory, perceptual speed and attention. It is assumed that cognitive impairments in patients with congestive heart failure may lead to deficits in medication-adherence and self-care abilities, resulting in increased healthcare costs. Recent studies reported performance improvements after cognitive training that transferred to new, untrained tasks and abilities in healthy subjects across a wide range of ages. This study investigates the effects of cognitive training in patients with congestive heart failure.
详细描述
Cognitive functions of patients with congestive heart failure (NYHA II-III) before (pretest) and after (posttest) cognitive-training intervention are investigated. Changes in cognitive functions are compared to changes in two control groups: 1) age and gender matched active control group 2) age and gender matched passive waiting list control group. The neuropsychological test battery applied at pretest and posttest includes measures of episodic memory, working memory, short-term memory, executive functions, perceptual speed and intelligence. In addition, the investigators apply standardized questionnaires of self-assessed quality of life, cognitive functioning in daily life, selfcare, and psychological well-being (depression, anxiety and personality). Relevant physiological data such as ejection fraction, heartrate, N-terminal pro brain natriuretic peptide (NT-pro-BNP) as well as drug blood level are recorded.
研究者
Sonja Wedegärtner
Dipl. Psych.
Universität des Saarlandes
入排标准
入选标准
- •Congestive heart failure
- •NYHA II-III
排除标准
- •Psychosis
- •Major depression
- •Reanimation (\<3month)
- •Patients with assist device system
结局指标
主要结局
Training effects
时间窗: 3 weeks
Improvement in performance in the last trainingssession compared with the performance in the first trainingssession. Performance will be assessed by computesoftware.
次要结局
- Transfer effects(5 weeks)
- Changes in quality of life and psychological well-being(5 weeks)
- Long-term benefits of cognitive training in patients with congestive heart failure.(6 month)
- Compliance with medication(5 weeks)