Assessment of plasma expression level of some factors involved in chemo-radiotherapy resistance in response to radiotherapy in non-metastatic rectal cancer patients
Early Phase 1
Recruiting
- Conditions
- locally advanced rectal cancer.Malignant neoplasm of rectum
- Registration Number
- IRCT2016072618745N9
- Lead Sponsor
- Vice chancellor for research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 55
Inclusion Criteria
Patient with locally advanced rectal cancer; Patient with non-metastatic rectal cancer
Exclusion criteria: Patients with other cancers; Patients with renal and hepatic disorders
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The alteration of plasma expression level of the miRNAs. Timepoint: before and after irradation. Method of measurement: microarray technique.
- Secondary Outcome Measures
Name Time Method Plasma expression level of the genes. Timepoint: befor and after irradation. Method of measurement: Real-time PCR.