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临床试验/NCT06695546
NCT06695546
已完成
不适用

Evaluation of the Venous Excess Ultrasound Score (VExUS) After Circulating Volume Modification in Children. VExUS-Mod

University Hospital, Toulouse1 个研究点 分布在 1 个国家目标入组 67 人2024年12月10日

概览

阶段
不适用
干预措施
VExUS evaluation ultrasound
疾病 / 适应症
Blood Volume Expansion
发起方
University Hospital, Toulouse
入组人数
67
试验地点
1
主要终点
Change in VExUS score
状态
已完成
最后更新
3个月前

概览

简要总结

Venous overload has an impact on peripheral organ perfusion and on the short- and long-term prognosis of intensive care patients. The VExUS ultrasound score is a new tool whose parameters can be used to estimate this impact. This score was initially evaluated and validated on an adult population. ) In children, there is only one study looking at the use and applicability of this VExUS score, highlighting its feasibility in a paediatric population, as well as a possible correlation between elevated central venous pressure and altered renal Doppler (one of the score's components).

注册库
clinicaltrials.gov
开始日期
2024年12月10日
结束日期
2025年6月6日
最后更新
3个月前
研究类型
Observational
性别
All

研究者

责任方
Sponsor

入排标准

入选标准

  • Children aged between 1 and 18 years, receiving extrarenal purification with UF \> 10 ml/kg, bleeding \> 10 ml/kg or vascular filling \> 10 ml/kg

排除标准

  • Refusal of the patient or opposition of one or both holders of parental authority.
  • Minors with parental authority.
  • Ultrafiltration time \> 6h.
  • Curarized patient, known abnormality of the hepatorenal venous network.
  • Patient agitated or poor tolerance of the examination.
  • Parents under court protection, guardianship or curatorship.

研究组 & 干预措施

Experimental

Patients over one year of age treated at Toulouse University Hospital and receiving extrarenal purification, bloodletting or vascular filling \> 10 ml/kg.

干预措施: VExUS evaluation ultrasound

结局指标

主要结局

Change in VExUS score

时间窗: 10 minutes before en after the procedure of extrarenal purification, bloodletting or vascular filling

The correlation between ultrasound measurement of the VExUS score and the change in blood volume induced by extrarenal purification, bloodletting or vascular filling is studied. Ultrasound is performed before and after the procedure, each measure 3 times in succession, to establish the score.

研究点 (1)

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