Contact Lenses and Infiltrative Keratitis
Not Applicable
Completed
- Conditions
- Keratitis
- Interventions
- Device: senofilcon A
- Registration Number
- NCT02186431
- Lead Sponsor
- State University of New York College of Optometry
- Brief Summary
To quantify and compare baseline tear proteins and ocular response in contact lens wearers with a history of corneal infiltrative events, to those without a history of complications. This will be accomplished via measurement of select anti-inflammatory tear proteins before, during and after contact lens wear.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
- Soft contact lens wearers
- Healthy (control), or with history of infiltrative keratitis (case)
- Has a wearable pair of glasses
- Refractive error between +8.00 D and -12.00 D, with less than 1.50 D of astigmatism
Exclusion Criteria
- Smoker
- Pregnant or nursing
- Systemic disease that would effect tear proteins
- Punctal plugs
- Use of eye drops in the last week
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description without a history of corneal infiltrative events senofilcon A To quantify and compare baseline tear proteins and ocular response in contact lens wearers without a history of corneal infiltrative events. history of corneal infiltrative events senofilcon A To quantify and compare baseline tear proteins and ocular response in contact lens wearers with a history of corneal infiltrative events
- Primary Outcome Measures
Name Time Method Tear protein levels After 4-6 hours of daily wear and after one night extended wear
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
SUNY College of Optometry, Clinical Vision Research Center
🇺🇸New York, New York, United States