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Visual Outcomes Following Descemet Stripping Automated Endothelial Keratoplasty

Completed
Conditions
Corneal Endothelial Disorder
Registration Number
NCT03685734
Lead Sponsor
Centre Hospitalier Régional Metz-Thionville
Brief Summary

To assess objective and subjective visual outcomes achieved by patients with corneal endothelial dysfunction who have undergone surgical treatment with Descemet stripping automated endothelial keratoplasty (DSAEK).

Detailed Description

Since 2006, the technique by removing the Descemet membrane from the recipient cornea was renamed Descemet stripping automated endothelial keratoplasty (DSAEK). In recent years, DSAEK techniques have evolved, favoring increasingly thinner and finer grafts, known as ultrathin DSAEK (UT DSAEK), with the aim of obtaining better visual results.

Endothelial keratoplasty is now the most common surgical procedure used to treat endothelial dysfunction. The current study focused on assessing both objective and subjective visual quality outcomes following DSAEK.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
36
Inclusion Criteria
  • Clinical eligibility for DSAEK
  • Informed written consent
  • Successful completion of DSAEK procedure
  • Postoperative follow-up at least 1 year
  • Ability to respond to the questionnaire
Exclusion Criteria
  • Patients with clinical edematous cornea
  • With significant stromal opacity
  • With major disturbances of ocular surface
  • Previous corneal surgery

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Visual acuity1 year

Scored with reference to the logarithm of the minimum angle of resolution (logMAR) and its variation in line gain.

Secondary Outcome Measures
NameTimeMethod
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