The impact of frailty, activity levels and mitochondrial efficiency on post operative outcomes in older patients undergoing abdominal surgery

Not Applicable

Completed

• Conditions: Recovery from colorectal surgery; Frailty; Colorectal cancer; Inflammatory bowel disease; Diverticulitis; Colorectal surgery; Surgery - Other surgery

• Registration Number: ACTRN12618000045213
• Lead Sponsor: niversity of Otago Christchurch

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-15
• Study Completion: 2018-12-10
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Those included in this study will
•Be undergoing an elective colorectal surgical procedure within the next 6 months
•Be aged 65 years or over
•Be ambulatory, including with the use of walking aids such as sticks or frames

Exclusion Criteria

•Unable to obtain valid consent
•Stoma reversal surgery
•Non general-surgical abdominal procedures (ie vascular procedures)
•Non-ambulatory/mobilises in wheelchair
•Emergency surgery
•Date of recruitment less than 2 weeks before admission date
•Dermatitis or skin lesions of the upper limb that would prevent safe and comfortable wearing of the activity tracking device
•Regular participation in moderate to high intensity physical activity not detected by activity tracking device, such as cycling or swimming

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hospital length of stay. This includes time spent in tertiary referral centre (ie site of surgery) and time spent in primary rehabilitation hospital. [Day of discharge from rehabilitation hospital]

Secondary Outcome Measures

Name	Time	Method
Discharge destination[Day of discharge];Post operative complications. <br> - a standardised proforma has been designed for the study that includes surgical and medical complications. This data will be gathered prospectively during the inpatient postoperative stay combined with a review of medical records at 30 and 100 days. <br>Examples of complications on proforma include<br>SURGICAL COMPLICATIONS (graded clavien dindo I-V)<br>surgical site infection<br>ileus<br>anastomotic leak<br>bleeding<br>return to theatre<br>other<br>MEDICAL COMPLICATIONS<br>CVS (arrest, MI, DVT/PE, arrhythmia requiring intervention)<br>Respiratory (pneumonia)<br>Neurological (CVA, acute delirium)<br>Renal (AKI, UTI, failed TOV)<br>sepsis<br>unplanned ICU admission<br><br><br>[100 days following scheduled surgery];survival[100 days following scheduled surgery ];SF-12 (quality of life)[Post operative day 30];Fatigue (visual analogue scale)[Post operative day 30]