GLP-2 (Glucagonlike Peptide-2) and Blood Flow

Not Applicable

Completed

• Conditions: Regional Blood Flow
• Interventions: Other: Glucagonlike peptide

• Registration Number: NCT00540215
• Lead Sponsor: Glostrup University Hospital, Copenhagen

Brief Summary

It is the study aim to investigate the effect of glp-2 on blood flow in humans. we wish to study eventual changes in renal blood flow, carotic blood flow and cardiac out put.

GLP-2 will be administered subcutaneously, and the effect monitored by doppler ultra sound scannings and cotinuesly measuring of cardiac out put and blood pressure.

The study will include 15 healhty volunteers, 10 wil receive 450 nmol GLP-2 and 5 will receive 1 ml of isotonic saline (as baseline reference).

Detailed Description

se the above

Study Timeline

• Status Verified: 2007-10
• Study Start: 2007-10
• Study First Submitted: 2007-10-04
• Study First Submitted QC: 2007-10-04
• Study First Posted: 2007-10-05
• Primary Completion: 2008-01
• Study Completion: 2008-02
• Last Update Submitted: 2011-02-10
• Last Update Posted: 2011-02-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Age 20-60
• Healthy
• No medication
• Not pregnant

Exclusion Criteria

• All of the persons not meeting the abowe mentioned criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
1	Glucagonlike peptide	450 nmol GLP-2 SC
2	Glucagonlike peptide	1 ml isotonic saline SC

Primary Outcome Measures

Name	Time	Method
effect of glp-2	during study

Secondary Outcome Measures

Name	Time	Method
potential new ideas for further studies	months to years

Trial Locations

Locations (1)

Glostrup University Hospital; 🇩🇰 Glostrup, Region Hovedstaden, Denmark