Effect of the Enteric Hormone Glucagon-Like Peptide (GLP-2) on the Intestinal Blood Flow in Patients With Short Bowel Syndrome

Not Applicable

• Conditions: Short Bowel Syndrome
• Interventions: Drug: Placebo; Drug: GLP-2

• Registration Number: NCT00673751
• Lead Sponsor: Glostrup University Hospital, Copenhagen

Brief Summary

The aim of the study is to investigate the effect of the enteric hormone Glucagon-like Peptide (GLP-2) on patients with short bowel syndrome

Detailed Description

previous studies have shown that GLP-2 increases mesenteric blow flow, we wish to examine the effect of subcutaneus GLP-2 on patients with short bowl syndrome. The patients will single blinded been given 450 nmol GLP-2 and isotonic saline in order to act as their own reference.

Study Timeline

• Status Verified: 2008-05
• Study First Submitted: 2008-05-05
• Study First Submitted QC: 2008-05-06
• Last Update Submitted: 2008-05-06
• Study First Posted: 2008-05-07
• Last Update Posted: 2008-05-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

• clinical diagnose of short bowel syndrome 4 month of stable fase

Exclusion Criteria

• activity in IBD

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
2	Placebo	subcutaneous isotonic saline
1	GLP-2	subcutaneous GLP-2

Trial Locations

Locations (1)

Glostrup University Hospital; 🇩🇰 Glostrup, Region Hovedstaden, Denmark