Skip to main content
MedPathMedPath Home
Clinical Trials/NCT03017118
NCT03017118
Recruiting
Not Applicable

A Randomized Controlled Trial Using Turmeric for Patients With Basal Joint Arthritis

Massachusetts General Hospital1 site in 1 country60 target enrollmentAugust 9, 2017
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsThumb Osteoarthritis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Thumb Osteoarthritis
Sponsor
Massachusetts General Hospital
Enrollment
60
Locations
1
Primary Endpoint
Change in baseline pain intensity
Status
Recruiting
Last Updated
5 months ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.

Registry
clinicaltrials.gov
Start Date
August 9, 2017
End Date
January 1, 2028
Last Updated
5 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Neal Chung-Jen Chen

Medical Doctor

Massachusetts General Hospital

Eligibility Criteria

Inclusion Criteria

  • •40 years of age or older
  • •English fluency and literacy
  • •Seeking care for basal joint pain
  • •Tender over basal joint
  • •Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction)
  • •Radiographic evidence of Eaton stage 1 and 2 only

Exclusion Criteria

  • •Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment
  • •Inability or unwillingness to participate in a trial study
  • •Rheumatoid Arthritis or other inflammatory disorder diagnoses
  • •Post-traumatic osteoarthritis
  • •Patients on Coumadin/Steroids/NSAIDs/Tylenol
  • •Diabetes Mellitus
  • •Pregnant or lactating women
  • •Basal joint arthritis of Eaton stage 3
  • •Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)

Outcomes

Primary Outcomes

Change in baseline pain intensity

Time Frame: Enrollment, 6 weeks, and 3 months

0-10 ordinal rating of pain intensity

Change in baseline disability

Time Frame: Enrollment, 6 weeks, and 3 months

Disability measured by the QuickDASH

Study Sites (1)

Loading locations...

Similar Trials

Completed
Not Applicable
Bioavailability of Curcuminoids From Turmipure Gold® in Different Food MatricesHealthy
NCT06300021Givaudan France Naturals35
Terminated
Phase 1
Curcuma Longa L in Rheumatoid ArthritisRheumatoid Arthritis
NCT02543931University of Arizona3
Completed
Not Applicable
A Study to Evaluate the Effect of Turmeric in Healthy ParticipantsHealthy
NCT05535231Gaia Herbs Inc.14
Unknown
Phase 1
Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) ArthritisArthritis of Carpometacarpal Joint of Left ThumbArthritis of Carpometacarpal Joint of Right Thumb
NCT06359665Brent DeGeorge100
Completed
Not Applicable
A Clinical Trial to Evaluate the Chronic Safety and Tolerance of Turmipure Gold™ in Healthy SubjectsGastrointestinal ToleranceLiver FunctionKidney Function
NCT03945149Givaudan France Naturals60