Resistance and Aerobic Exercise With Nutritional Supplementation in Men and Women

Not Applicable

Completed

• Conditions: Obesity
• Interventions: Dietary Supplement: Whey protein supplementation with exercise; Other: Non protein supplementation with exercise (control)

• Registration Number: NCT00812409
• Lead Sponsor: Purdue University

Brief Summary

The purpose of this study is to identify the influence of resistance and aerobic exercise with different nutritional supplements in middle-aged men and women on various physiological measures. Throughout the study, the investigators examine body composition, body weight, food intake, fitness level, metabolism, and blood hormones.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-04
• Study First Submitted: 2008-12-18
• Study First Submitted QC: 2008-12-19
• Study First Posted: 2008-12-22
• Primary Completion: 2010-07
• Study Completion: 2010-09
• Status Verified: 2013-01
• Last Update Submitted: 2013-01-16
• Last Update Posted: 2013-01-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 580

Inclusion Criteria

• men and women age 35-65 yr
• body weight <300 lbs (136 kg)
• body mass index between 28 kg/m2 and 35 kg/m2
• fasting glucose <110 mg/dL
• blood pressure <160/100 mm Hg
• plasma total cholesterol <260 mg/dL
• LDL-cholesterol <160 mg/dL
• triacylglycerol <400 mg/dL
• not currently or previously following a weight loss diet or other special/non-balanced diet (in the past 6 months)
• <1 hour/week of habitual aerobic exercise training and no resistance
• exercise training (in the past 6 months)

Exclusion Criteria

• men and women age < 35 yr or >65 yr
• body weight >300 lbs (136 kg)
• body mass index between <28 kg/m2 or >35 kg/m2
• fasting glucose >110 mg/dL
• blood pressure >160/100 mm Hg
• plasma total cholesterol >260 mg/dL
• LDL-cholesterol >160 mg/dL
• triacylglycerol >400 mg/dL
• currently or previously following a weight loss diet or other special/non- balanced diet (in the past 6 months)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
4	Whey protein supplementation with exercise	High protein supplement with resistance and aerobic exercise.
3	Whey protein supplementation with exercise	Moderate protein supplement with resistance and aerobic exercise.
1	Non protein supplementation with exercise (control)	Control group: non-protein supplement with resistance and aerobic exercise.
2	Whey protein supplementation with exercise	Low protein supplement with resistance and aerobic exercise.

Primary Outcome Measures

Name	Time	Method
Influence of resistance and aerobic exercise and whey protein on body weight and body composition (fat mass and fat free mass).	36 weeks

Secondary Outcome Measures

Name	Time	Method
Influence of resistance and aerobic exercise and whey protein on dietary and macronutrient intakes, insulin-mediated glucose metabolism, physical fitness and markers of metabolic and cardiovascular health.	36 weeks

Trial Locations

Locations (1)

Purdue University; 🇺🇸 West Lafayette, Indiana, United States