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Safety and Efficiency of Photodynamic Therapy for Rectal Cancer

Phase 2
Suspended
Conditions
Advanced Rectal Cancer
Interventions
Procedure: Photodynamic therapy
Registration Number
NCT01872104
Lead Sponsor
li xiong
Brief Summary

This research is a prospective randomized controlled trial.It aimed to determine longterm outcomes and factors associated with increased survival after photodynamic therapy (PDT) through colonscopy compared with chemotherapy alone in patients presenting with advanced rectal cancer.

Detailed Description

Not available

Recruitment & Eligibility

Status
SUSPENDED
Sex
All
Target Recruitment
100
Inclusion Criteria
  • 1.Patients with advanced rectal cancer 2.Patients are willing to join in this clinical trial.
Exclusion Criteria
  • 1.Patients with advanced rectal cancer can not suffer PDT procedure. 2.Allergy to photosensitizer

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
PDT and ChemotherapyPhotodynamic therapyGroup that not only be scheduled to undergo chemothrapy using FOLFOX4 protocol,but also receive colonscopy-assisted PDT.
Primary Outcome Measures
NameTimeMethod
Survival rateone month
Secondary Outcome Measures
NameTimeMethod
Progression-free survivalOne month

Trial Locations

Locations (1)

The Second Xiangya Hospital of Central South University

🇨🇳

Changsha, Hunan, China

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