Early diagnosis of coeliac disease in the Preventive Youth Health Care Centres in the Netherlands
- Conditions
- Coeliac disease, Active case finding, Secondary prevention, Preventive Youth Health Care Centre. Coeliakie, vroege opsporing, secundaire preventie, jeugdgezondheidszorg
- Registration Number
- NL-OMON20983
- Lead Sponsor
- eiden University Medical Center; Dutch Coeliac Patients Society; Preventive Youth Health Care Centres;
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 15000
Inclusion Criteria
Age 12 months to 4 years;
Not diagnosed with CD;
Exclusion Criteria
No informed consent;
Asymptomatic children;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To establish the feasibility, effectiveness and costs of early case finding of CD in children attending the YHCCs in a well described region in the Netherlands, using a POC test for TG2A determination. Comparison with outcome of current health care.
- Secondary Outcome Measures
Name Time Method Children already diagnosed with CD prior to the study (n); <br /><br>Time investment by medical and nursing staff at the YHCCs (sec); <br /><br>Costs of the investigational strategy (time, materials) (€); <br /><br>Cost-effectiveness of the investigational strategy; <br /><br>Acceptance of active case finding by the Dutch population.