ISRCTN14384676已完成不适用
Early Diagnosis of Necrotising EnteroColitis: a prospective observational multicentre trial in neonates presenting with acute abdome
Island Hospital (Inselspital) (Switzerland)0 个研究点目标入组 50 人开始时间: 2007年7月2日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •Current information as of 11/05/2009:
- •1. Newborns below 36 days of postnatal age
- •2. Acute abdomen with suspicion of NEC
- •3. Gestational age below 34 weeks of gestational age (GA)
- •4. Written parental consent
- •Initial information at time of registration:
- •1. Newborns below 36 days of postnatal age
- •2. Clinical, laboratory and radiological assessment for an acute abdomen possibly due to NEC
- •3. For the diagnosis of NEC among infants presenting with an acute abdomen, the criteria of Bell, modified by Walsh and Kliegman and adopted by the Vermont Oxford Network:
- •3.1. The presence of one or more of the following clinical signs:
- •3.1.1. Feeding intolerance with bilious gastric aspirate or emesis
- •3.1.2. Abdominal distension
- •3.1.3. Occult or gross blood in stool (no fissure)
- •3.2. And one or more of the three following radiographic findings:
- •3.2.1. Pneumatosis intestinalis
- •3.2.2. Hepato-biliary gas
- •3.2.3. Pneumoperitoneum
排除标准
- •Current information as of 11/05/2009:
- •1. Age above 35 days of postnatal age
- •2. Patients that had undergone surgery one week prior to onset of the disease
- •Initial information at time of registration:
- •1. Age above 35 days of postnatal age
- •2. Patients that had undergone surgery one week prior to onset of the disease
- •3. Focal intestinal perforation consistent with:
- •3.1. Visual aspect of the bowel at the time of surgery and post-mortem
- •3.2. Absence of inflammation and coagulative necrosis in histological findings
研究者
相似试验
Unknown
不适用
Monitoring Necrotizing Enterocolitis in Premature InfantsNecrotizing EnterocolitisNCT01287559Spectros Corporation100
已完成
不适用
ovel diagnostic markers for necrotising enterocolitis in the premature infantnecrotising enterocolitis10017969NL-OMON34937niversitair Medisch Centrum Groningen40
已完成
不适用
Onderzoek naar nieuwe diagnostische markers voor vroeg-diagnostiek van necrotiserende enterocolitis bij pasgeborenen.ecrotizing enterocolitis (NL: necrotiserende enterocolitis)acute abdomen in neonates (NL: neonaten met acute buik)NL-OMON26582MC Groningen40
尚未招募
不适用
Early diagnosis of coeliac disease in the Preventive Youth Health Care Centres in the NetherlandsNL-OMON20983eiden University Medical Center; Dutch Coeliac Patients Society; Preventive Youth Health Care Centres;15,000
招募中
不适用
Early diagnosis of coeliac disease in the Preventive Youth Health Care Centres in the Netherlands.autoimmune diseaseGlutenintolerance10025477NL-OMON52929eids Universitair Medisch Centrum5,436