Clinical Evaluation of Leech Therapy in the Treatment of Knee Osteoarthritis

Phase 2

Completed

• Conditions: Knee Osteoarthritis
• Interventions: Biological: Hirudinaria granulosa, qurse mafasil

• Registration Number: NCT02612974
• Lead Sponsor: Hamdard University

Brief Summary

This study has been designed to conduct as Randomized comparative clinical study.

Detailed Description

Two groups, group B received Qurse Mafasil tablet orally two tablets two times daily for 8 weeks while group A received Leech therapy once weekly for 8 weeks along with Qurse mafasil.

Study Timeline

• Study Start: 2010-01
• Primary Completion: 2012-03
• Study Completion: 2012-06
• Status Verified: 2015-11
• Study First Submitted: 2015-11-20
• Study First Submitted QC: 2015-11-23
• Last Update Submitted: 2015-11-23
• Study First Posted: 2015-11-24
• Last Update Posted: 2015-11-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• knee osteoarthritis

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Exclusion Criteria

• pregnancy,
• lactation,
• anaemia

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group B	Hirudinaria granulosa, qurse mafasil	Qurse mafasil only given
Group A	Hirudinaria granulosa, qurse mafasil	Hirudinaria granulosa and Qurse mafasil are given

Primary Outcome Measures

Name	Time	Method
KOOS Score	end of 6 weeks
VAS	end of 6 weeks
Active Range of Motion	end of 6 weeks
Knee circumference	end of 6 weeks
15 m walking time test	end of 6 weeks

Secondary Outcome Measures

Name	Time	Method
KOOS subscores	end of 6 weeks