Prospective observational study investigating Chemotherapies in untreated patients withnewly diagnosed primary CNS-Lymphoma (PCNSL)
Recruiting
- Conditions
- Primary CNS-Lymphoma
- Registration Number
- DRKS00011220
- Lead Sponsor
- Knappschaftskrankenhaus Bochum-Langendreer
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
PZNSL confirmed in histology, cytology or immunocytology
No Lymphoma manifestations outside the CNS
No contraindications for intensive chemo therapy
Consent to paticipation
Exclusion Criteria
Lymphoma manifestations outside the CNS,
preceding or planned WBRT,
previous PCNSL therapy other than corticosteroids,
active uncontrolled infection,
immunosuppression, concomitant immunsuppressive therapy
status post organ Transplantation,
HIV infection,
concomitant malignancy in the last 5 years other than basal cell carcinoma or carcinoma in situ of the Cervix,
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ot applicable.<br>The goal ist to evaluate the different protocols of chemotherapy in effectiveness (over all survival, progression free survival)and tolerance (toxicity, therapy discontinuations)
- Secondary Outcome Measures
Name Time Method