Optimizing Meal and Snack Timing to Promote Health

Not Applicable

Completed

• Conditions: Dietary Modification
• Interventions: Dietary Supplement: 10 + 20 g protein consumption; Other: 10 g protein breakfast; Other: 30 g protein breakfast

• Registration Number: NCT02506218
• Lead Sponsor: Purdue University

Brief Summary

This study will be conducted using standardized techniques to collect blood samples via an acute, randomized, cross-over design. Subjects will be provided all of their meals the day prior to testing and participate in 3 testing days with a minimum of 1 week break between testing days and a maximum time commitment of 7 weeks. A trained phlebotomist will place a catheter and collect blood samples from an antecubital vein using sterile techniques.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-04
• Study First Submitted: 2015-06-24
• Study First Submitted QC: 2015-07-21
• Study First Posted: 2015-07-23
• Primary Completion: 2016-03
• Study Completion: 2016-03
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-09
• Last Update Posted: 2018-01-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

25-39 years old

• BMI between 22-37 kg/m2
• Weight stable (± 4.5 kg) for the previous 3 months
• Not currently (or within the past 6 months) following a vigorous exercise regimen or weight loss program
• No acute illness
• Not smoking
• Not diabetic
• Not pregnant or planning pregnancy in the next 3 months
• Lactose tolerant
• Willing to limit purposeful activity for 48 hours prior to each testing day
• Willing to consume study foods and beverages.

Exclusion Criteria

• <25 or >39 years old, BMI <22 or >37 kg/m2
• Currently (or within the past 6 months) following a vigorous exercise regimen greater than -3 - 45 minute exercise sessions per week
• Currently following a weight loss program where subject has lost greater than 4.5 kg
• Acute illness
• Smoking
• Diabetic
• Pregnant or planning pregnancy in the next 3 months
• Lactose intolerant
• Unwilling to consume study foods and beverages
• Peri and post-menopausal women.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
10 + 20 g protein consumption	10 + 20 g protein consumption	10 g breakfast followed by the consumption of a 20g whey protein shake
10 g protein breakfast	10 g protein breakfast	-
30 g protein breakfast	30 g protein breakfast	-

Primary Outcome Measures

Name	Time	Method
Plasma amino acid concentration	7 weeks	Peak plasma concentration of amino acids

Secondary Outcome Measures

Name	Time	Method
Blood glucose concentration	7 weeks	Area under the curve of blood glucose

Trial Locations

Locations (1)

Purdue University; 🇺🇸 West Lafayette, Indiana, United States