NL-OMON56016招募中不适用
Protein supplementation and exercise training to increase muscle protein synthesis rates in patients with advanced chronic kidney disease - Protein and Exercise Training in chronic kidney disease
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 62
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. In order to be eligible to participate in this study, a patient with CKD
- •must meet all of the following criteria:
- •(e)glomerular filtration rate (GFR) <45 ml/min/1.73m2
- •Age: 18 - 80 y
- •Able to provide written informed consent
- •2. In order to be eligible to participate in this study, a healthy subject must
- •meet all of the following criteria:
- •(e)GFR >60 ml/min//1.73m2 without albuminuria
- •Age: 18 - 80 y
- •Able to provide written informed consent
排除标准
- •Insulin-dependent diabetes mellitus or two or more oral glucose lowering
- •medications
- •Active inflammatory disease / malignancies
- •Uncontrolled hypertension (>160/100mm Hg), unstable angina pectoris, or
- •Pulmonary disease restricting exercise performance (e.g. COPD)
- •A history of neuromuscular problems
- •Cognitive Impairment
- •Diagnosed GI tract diseases / dysphagia
- •Allergies to milk proteins / Lactose intolerance
- •Pregnancy
- •Hospitalization <1 months prior to study period
- •Participation in any structured exercise program
- •Any medications known to affect protein metabolism (i.e. corticosteroids or
- •prescription strength acne medications).
- •Use of DOAC, vitamin-K-antagonist, or multiple anticoagulants.
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