Krachttraining en eiwitsuppletie ter preventie van bijwerkingen van hormonale behandeling bij mannen met prostaatkanker.
Recruiting
- Conditions
- prostate cancer, androgen deprivation therapy, muscle mass, resistance exercise, protein supplementationprostaatkanker, androgen deprivatie therapie, spiermassa, krachtttraining, eiwitsuppletie
- Registration Number
- NL-OMON20332
- Lead Sponsor
- Maastricht University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 208
Inclusion Criteria
Men with PC on ADT for progressive disease (metastatic disease or increasing PSA level after primary treatment)
Exclusion Criteria
- Allergies to whey protein
- Lactose intolerance
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Body composition: body weight, body height, BMI, waist circumference, muscle mass, fat mass, body fat distribution assessed with DEXA and quadriceps muscle cross-sectional area measured by CT scanning of the upper leg.
- Secondary Outcome Measures
Name Time Method Muscle strength: measured by 1-RM<br /><br>„h Maximal oxygen uptake (VO2max)<br /><br>„h Physical performance (timed Up and Go test, 30 seconds chair stand test, stair climbing test)<br /><br>„h Level of independent living (The Impact on Participation and Autonomy (IPA) Questionnaire) (Appendix F1.2)<br /><br>„h HRQoL (EORTC QLQ-C30, EORTC QLQ-PR25) (Appendix F1.3 en F1.4)<br /><br>„h Fatigue (Multidimensional Fatigue Inventory (MFI) (Appendix F1.5)<br /><br>„h Blood results (PSA, testosterone, LDH, alkalis phosphatase, triglycerides, cholesterol (HLD, LDL and total), glucose, creatinine, liver function)<br /><br>„h Adverse events (Number, kind and seriousness)