Comparing the effective post-operative onset of pain effect of two drug combinations Bupivacaine with Fentanyl and Bupivacaine with Dexmedetomidine in lower limb surgeries

Phase 4

Recruiting

• Conditions: Medical and Surgical, (2) ICD-10 Condition: M858||Other specified disorders of bonedensity and structure,

• Registration Number: CTRI/2021/03/032274
• Lead Sponsor: Aarupadai Veedu Medical college Hospital

Brief Summary

Summary of this study is to compare the Post-operative onset of pain between the two Intrathecal drug combinations i.e. Bupivacaine with Fentanyl versus Bupivacaine with Dexmedetomidine.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-30
• Last Update Posted: 2022-04-07

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Patients of age 18-65yrs of either sex Orthopedic and General Surgeries lasting for 1-2 hrs Patients of ASA-I & II Patients weighing 50-80kgs.

Exclusion Criteria

Hypersensitivity to any of the drugs Uncontrolled Diabetes Mellitus and Hypertension Renal and Liver failures Cardiac dysrhythmias Coagulopathies.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare Post-operative Pain Analgesia of Intrathecal Bupivacaine with Fentanyl versus Intrathecal Bupivacaine with Dexmedetomidine	12 HOURS

Secondary Outcome Measures

Name	Time	Method
Sensory blockade	Motor blockade

Trial Locations

Locations (1)

Aarupadai Veedu Medical college & Hospital; 🇮🇳 Pondicherry, PONDICHERRY, India

Aarupadai Veedu Medical college & Hospital

🇮🇳Pondicherry, PONDICHERRY, India

Dr P Arjun

Principal investigator

9849549505

arjun.1115@gmail.com