Association of Plasma PTX3 Concentration and Outcomes of STEMI
- Conditions
- Coronary; IschemicSTEMI
- Interventions
- Other: Plasma PTX3 concentration
- Registration Number
- NCT03894176
- Lead Sponsor
- Indonesian Cardiovascular Research Center
- Brief Summary
335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method. The angiographic and clinical outcomes were evaluated according to the PTX3 concentration.
- Detailed Description
335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method using human PTX3 kit. Blood was drawn at the emergency department before primary PCI. The angiographic and clinical outcomes were evaluated and analyzed according to the PTX3 concentration. The angiographic outcome were thrombus grade on initial angiogram and final TIMI flow. The clinical outcome were ECG resolution after primary PCI and all-cause death at 30 days. The plasma PTX3 concentration was then compared based on the outcomes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 335
- Patients with acute STEMI with symptom onset <12 h undergoing primary PCI
- Acute STEMI patients who received fibrinolytic therapy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description PTX3 concentration Plasma PTX3 concentration First quartile, second quartile, third quartile and fourth quartile of PTX3 in ng/mL
- Primary Outcome Measures
Name Time Method The proportion of thrombus grade 4&5 and final TIMI flow <3 Intraprocedure PTX3 concentration was compared based on the outcome
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Indonesian Cardiovascular Research Center
🇮🇩Jakarta, DKI Jakarta, Indonesia