Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications

Completed

• Conditions: Transfusion; Spinal Fusion; Pulmonary Complication
• Interventions: Procedure: transfusion

• Registration Number: NCT05661838
• Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary

Elective spine surgery is associated with a high incidence of perioperative complications, including peri- and postoperative pulmonary complications (PPCs), which occur in nearly 4% of patients. More than 40% of all deaths after elective spine surgery are attributed to PPCs. However, whether it influences risk of other PPCs is unclear.

Detailed Description

Not available

Study Timeline

• Status Verified: 2013-08
• Study Start: 2013-08-01
• Primary Completion: 2020-10-31
• Study Completion: 2020-10-31
• Study First Submitted: 2022-12-15
• Study First Submitted QC: 2022-12-21
• Last Update Submitted: 2022-12-21
• Study First Posted: 2022-12-22
• Last Update Posted: 2022-12-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 272

Inclusion Criteria

• Patients were included if they underwent elective spine surgery (e.g. multi-segmental thoracic, lumbar, or thoracolumbar spine surgery) at the Second Hospital of Zhejiang University School of Medicine from August 1, 2013 to October 31, 2020

Exclusion Criteria

• combined anterior-posterior surgery
• growth rod adjustment surgery
• spinal tumor.
• surgery took fewer than 3 hours.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
non-PPCs group	transfusion	Patients without PPCs (Pleural effusion, Pulmonary atelectasis, Pulmonary infection)
PPCs group	transfusion	Patients with PPCs (Pleural effusion, Pulmonary atelectasis, Pulmonary infection)

Primary Outcome Measures

Name	Time	Method
Correlation between blood transfusion and postoperative pulmonary complications	28 days after surgery	Correlation between blood transfusion and postoperative pulmonary complications

Trial Locations

Locations (1)

The Second Affiliated Hospital of Zhejiang University anesthesiology department; 🇨🇳 Hangzhou, Zhejiang, China