Stored RBC Transfusion and Immonomodulation

Not Applicable

Completed

• Conditions: Infections
• Interventions: Other: Fresh RBC; Other: Old RBC

• Registration Number: NCT01976234
• Lead Sponsor: Università degli Studi di Ferrara

Brief Summary

Transfusion of RBC is associated with post operative infections. Our hypothesis is that stored blood could be related with increased post operative infection risk. Surgical patients transfused during the operation or immediately after will be included in our study. Patients will receive fresh or old blood during the whole recovery.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-09
• Study First Submitted: 2013-09-30
• Study First Submitted QC: 2013-10-29
• Study First Posted: 2013-11-05
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Status Verified: 2016-02
• Last Update Submitted: 2016-02-02
• Last Update Posted: 2016-02-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 181

Inclusion Criteria

• Patients transfused during or in 24h after surgical operation

Exclusion Criteria

• Patients transfused during the 30 days before the operation
• Immunodepressed patients
• Infections during the 30 days before operations
• Emergency surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Fresh group	Fresh RBC	Fresh group will receive RBC stored for less than 14 days
Old group	Old RBC	Old group will receive RBC stored for 14 days or more

Primary Outcome Measures

Name	Time	Method
Incidence of infections	28 days

Trial Locations

Locations (1)

Sant'Anna Hospital; 🇮🇹 Ferrara, Italy