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临床试验/NCT02555241
NCT02555241已完成不适用

Instructional Programming to Promote the Emergence of Generative Language in Children With Autism Spectrum Disorder

Emory University0 个研究点目标入组 9 人开始时间: 2015年9月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
9
主要终点
Emergence of intraverbal responses

研究概览

简要总结

The purpose of this study is to investigate the effects of several applied behavior teaching procedures on the use of multi-word utterances by children with autism.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
4 Years 至 6 Years(Child)
性别
All
接受健康志愿者
是

入选标准

  • •Diagnosis of Autism Spectrum Disorder (ASD)
  • •Provide a diagnostic report confirming a diagnosis of ASD and/or obtain a total raw score of 15 or greater on the Social Questionnaire Lifetime Form (SCQ)
  • •Speaks primarily in one word utterances
  • •English as their primary language
  • •Follows simple 1-step instructions
  • •Transportation/availability to attend 3, 1-hour sessions each week for 12 weeks

排除标准

  • •Children with significant problem behavior that interferes with structured intervention

研究组 & 干预措施

One Baseline Session

Experimental

Designated for participants #1 and #2. Participants complete 1 Baseline Session followed immediately by 12 weeks of standard treatment. Standard treatment will require the participant to attend clinic-based treatment sessions for 1 hour per day, 3 days per week, for 12 weeks. Standard treatment will consist of 3 components: mand training, matrix training, and stimulus equivalence training.

干预措施: Mand Training (Behavioral)

One Baseline Session

Experimental

Designated for participants #1 and #2. Participants complete 1 Baseline Session followed immediately by 12 weeks of standard treatment. Standard treatment will require the participant to attend clinic-based treatment sessions for 1 hour per day, 3 days per week, for 12 weeks. Standard treatment will consist of 3 components: mand training, matrix training, and stimulus equivalence training.

干预措施: Matrix (Behavioral)

One Baseline Session

Experimental

Designated for participants #1 and #2. Participants complete 1 Baseline Session followed immediately by 12 weeks of standard treatment. Standard treatment will require the participant to attend clinic-based treatment sessions for 1 hour per day, 3 days per week, for 12 weeks. Standard treatment will consist of 3 components: mand training, matrix training, and stimulus equivalence training.

干预措施: Stimulus Equivalence Training (Behavioral)

Two Baseline Sessions

Experimental

Designated for participants #3 and #4. Participants complete a Baseline Session followed by a 12 week wait period before repeating a Baseline Session followed immediately by 12 weeks of standard treatment. Standard treatment will require the participant to attend clinic-based treatment sessions for 1 hour per day, 3 days per week, for 12 weeks. Standard treatment will consist of 3 components: mand training, matrix training, and stimulus equivalence training.

干预措施: Mand Training (Behavioral)

Two Baseline Sessions

Experimental

Designated for participants #3 and #4. Participants complete a Baseline Session followed by a 12 week wait period before repeating a Baseline Session followed immediately by 12 weeks of standard treatment. Standard treatment will require the participant to attend clinic-based treatment sessions for 1 hour per day, 3 days per week, for 12 weeks. Standard treatment will consist of 3 components: mand training, matrix training, and stimulus equivalence training.

干预措施: Matrix (Behavioral)

Two Baseline Sessions

Experimental

Designated for participants #3 and #4. Participants complete a Baseline Session followed by a 12 week wait period before repeating a Baseline Session followed immediately by 12 weeks of standard treatment. Standard treatment will require the participant to attend clinic-based treatment sessions for 1 hour per day, 3 days per week, for 12 weeks. Standard treatment will consist of 3 components: mand training, matrix training, and stimulus equivalence training.

干预措施: Stimulus Equivalence Training (Behavioral)

Three Baseline Sessions

Experimental

Designated for participants #5 and #6. Participants complete a Baseline Session followed by two repetitions of the Baseline Session (each 12 weeks apart) and 12 weeks of standard treatment immediately following the third session. Standard treatment will require the participant to attend clinic-based treatment sessions for 1 hour per day, 3 days per week, for 12 weeks. Standard treatment will consist of 3 components: mand training, matrix training, and stimulus equivalence training.

干预措施: Mand Training (Behavioral)

Three Baseline Sessions

Experimental

Designated for participants #5 and #6. Participants complete a Baseline Session followed by two repetitions of the Baseline Session (each 12 weeks apart) and 12 weeks of standard treatment immediately following the third session. Standard treatment will require the participant to attend clinic-based treatment sessions for 1 hour per day, 3 days per week, for 12 weeks. Standard treatment will consist of 3 components: mand training, matrix training, and stimulus equivalence training.

干预措施: Matrix (Behavioral)

Three Baseline Sessions

Experimental

Designated for participants #5 and #6. Participants complete a Baseline Session followed by two repetitions of the Baseline Session (each 12 weeks apart) and 12 weeks of standard treatment immediately following the third session. Standard treatment will require the participant to attend clinic-based treatment sessions for 1 hour per day, 3 days per week, for 12 weeks. Standard treatment will consist of 3 components: mand training, matrix training, and stimulus equivalence training.

干预措施: Stimulus Equivalence Training (Behavioral)

结局指标

主要结局

Emergence of intraverbal responses

时间窗: Baseline (Up to 24 Weeks), End of Standard Treatment (Up to 36 weeks)

The goal of intervention is the mastery of 80% of evaluated intraverbal responses (2 for each target, 18 total).

Change in Mean Length of Utterances (MLU) during manding

时间窗: Baseline (Up to 24 Weeks), End of Standard Treatment (Up to 36 weeks)

The mean length of utterances (MLU) during manding will be evaluated in a 10 minute probe. The goal of intervention is to increase of MLU to an average of 3 words per mand.

Acquisition of noun-verb and color-shape combinations during tacting

时间窗: Baseline (Up to 24 Weeks), End of Standard Treatment (Up to 36 weeks)

The goal of intervention is mastery of 80% of evaluated noun-verb and color-shape targets.

次要结局

  • Change in Macarthur Bates-Communicative Development Inventory (CDI) Score(Baseline (Up to 24 Weeks), End of Standard Treatment (Up to 36 weeks))
  • Observe overall improvements in pragmatic language within social/play interactions with parents/caregivers, as measured on the Direct Observation of Spoken Language (DOSL).(Baseline (Up to 24 Weeks), End of Standard Treatment (Up to 36 weeks))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Alice Shillingsburg

Assistant Professor

Emory University

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