An Intervention to Reduce Inappropriate Medications in Long-term Care Residents With Severe Dementia

Not Applicable

Completed

• Conditions: Inappropriate Prescribing; Dementia
• Interventions: Behavioral: Knowledge exchange

• Registration Number: NCT03539276
• Lead Sponsor: CHU de Quebec-Universite Laval

Brief Summary

An education intervention to promote medication reviews and interdisciplinary discussions within long-term care facilities with the aim of improving medication regimen among residents with severe dementia

Detailed Description

A quasi-experimental study in three long-term care facilities. The intervention comprises an information leaflet for families of residents, a 90-minute knowledge exchange session for general practitioners, pharmacists and nurses and a list of "generally", "sometimes", and "exceptionally" appropriate medications for severe dementia residents

Study Timeline

• Study Start: 2014-03
• Primary Completion: 2014-10
• Study Completion: 2015-12
• Status Verified: 2018-05
• Study First Submitted: 2018-05-16
• Study First Submitted QC: 2018-05-25
• Study First Posted: 2018-05-29
• Last Update Submitted: 2018-05-30
• Last Update Posted: 2018-06-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• diagnosis of dementia of any etiology
• severe dementia

Exclusion Criteria

• admission less than 2 months before intervention

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
Post-intervention	Knowledge exchange	One 90-minute interdisciplinary knowledge exchange including the provision of a validated list of appropriate and inappropriate medications for severe dementia long-term care residents.

Primary Outcome Measures

Name	Time	Method
Medication regimen	Four months post intervention	Active prescriptions

Secondary Outcome Measures

Name	Time	Method
Level of pain	Four months post intervention	Pain Assessment Checklist for Seniors with Limited Ability to Communicate (PACSLAC).; The French version of the PACSLAC tool is a validated observational scale in use in Quebec to assess discomfort / pain.; One point is added to the score for each PACSLAC item (n=60) observed over a 15-minute observation period; the sum of the four 15-minute observation periods gives the total score. The total score ranges from zero to sixty where zero represents no discomfort or pain and sixty a very high level of discomfort or pain.
Level of agitation	Four months post intervention	Cohen-Mansfield Agitation Inventory () measures level of agitation. Sum of the number of times the Cohen-Mansfield Agitation Inventory items were observed during the four 15-minute observation periods.. The total score ranges from zero to one hundred where zero represents no agitation and one hundred a very high level of agitation.

Trial Locations

Locations (1)

Centre intégré universitaire de santé et de services sociaux de la Capitale-Nationale; 🇨🇦 Québec, Canada