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Clinical Trials/NCT01806103
NCT01806103
Completed
N/A

Reducing Inappropriate Prescribing of Antibiotics by Primary Care Clinicians

Children's Hospital of Philadelphia1 site in 1 country170 target enrollmentJune 2010

Overview

Phase
N/A
Intervention
Not specified
Conditions
Acute Sinusitis
Sponsor
Children's Hospital of Philadelphia
Enrollment
170
Locations
1
Primary Endpoint
Reduction in the rate of broad-spectrum antibiotic prescribing for targeted conditions for which narrow-spectrum antibiotic therapy is indicated
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

The purpose of the study is to determine if physician education coupled with audit and feedback of antibiotic prescribing can improve antibiotic prescribing by primary care clinicians.

Detailed Description

Using a large, diverse pediatric primary care network sharing a comprehensive electronic health record (EHR), a cluster-randomized trial will be performed to determine the effectiveness of an outpatient antimicrobial stewardship bundle, including treatment guidelines coupled with audit and feedback of physician prescribing, to curb inappropriate antibiotic prescribing for respiratory tract infections. Aim 1: To determine the impact of an outpatient antimicrobial stewardship bundle within a pediatric primary care network on antibiotic prescribing for conditions for which antibiotics are not indicated. Hypothesis: Antimicrobial stewardship will decrease rates of antibiotic prescribing for conditions for which antibiotics are not indicated. Aim 2: To determine the impact of an outpatient antimicrobial stewardship bundle within a pediatric primary care network on broad-spectrum antibiotic prescribing for conditions for which narrow-spectrum antibiotics are indicated. Hypothesis: Antimicrobial stewardship will decrease the rate of broad-spectrum antibiotic prescribing for conditions for which narrow-spectrum antibiotics are indicated.

Registry
clinicaltrials.gov
Start Date
June 2010
End Date
December 2012
Last Updated
13 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Primary care pediatric practices within the CHOP Care Network

Exclusion Criteria

  • Academic primary care pediatric practices within the CHOP Care Network
  • Providers entering a practice after the start of the intervention
  • Providers with less than 25 antibiotic prescriptions in the 6 months prior to the start of the intervention

Outcomes

Primary Outcomes

Reduction in the rate of broad-spectrum antibiotic prescribing for targeted conditions for which narrow-spectrum antibiotic therapy is indicated

Time Frame: from 20 months prior through 13 months post intervention

The primary outcome measure seeks to determine if the incorporation of treatment guidelines coupled with audit and feedback of physician prescribing can reduce the the rate of antibiotic prescribing for targeted conditions for which antibiotic therapy is not indicated.

Secondary Outcomes

  • The rate of antibiotic prescribing for targeted conditions for which antibiotic therapy is not indicated(from 20 months prior through 13 months post intervention)

Study Sites (1)

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