ISRCTN11946807
Completed
未知
ongitudinal study of physiological and immunological responses to COVID-19/SARS-CoV-2 infection in a population based study – Children of the 90s
niversity of Bristol0 sites372 target enrollmentNovember 23, 2020
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- COVID-19 (SARS-CoV-2 infection)
- Sponsor
- niversity of Bristol
- Enrollment
- 372
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Participants of the ALSPAC cohort meeting the following criteria:
- •1\. Aged 25 or over
- •2\. Undergone SARS\-CoV\-2 antibody testing through the ALSPAC SARS\-CoV\-2 serology study (IRAS 289493\)
- •3\. Individuals who, through self\-report or through linkage to official health records, are identified as being highly likely to have had COVID\-19 infection (from either positive SARS\-CoV\-2 PCR test performed at NHS care facility, COVID\-19 testing site or home testing)
- •4\. Individuals who have been told by a physician that, in the opinion of that doctor, they have had a clinical illness likely to be COVID\-19
- •Control participants
- •5\. Aged 25 or over
- •6\. Individuals who self\-report as not experiencing symptoms of COVID\-19 via the symptom survey
- •7\. Self\-report as not having had positive SARS\-CoV\-2 molecular test
- •8\. Are confirmed SARS\-CoV\-2 seronegative at Visit 1
Exclusion Criteria
- •Exclusion criteria for both controls and cases:
- •1\. Do not wish to participate in this research study
- •2\. Participants taking blood thinners or blood\-thinning agents (e.g. warfarin) or with a known clotting disorder or other reason unable to provide a blood sample
- •3\. Not willing to provide blood samples
- •4\. Do not meet eligibility criteria for respective arm
Outcomes
Primary Outcomes
Not specified
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